The coloured markup was created by Jalview (Michele Clamp)

Alignments are coloured using the ClustalX scheme in Jalview:

.Glycine (G)
.Proline (P)
.Small and hydrophobic (A,V,L,I,M,F,W)
.Hydroxyl and amine amino acids (S,T,N,Q)
.Charged amino-acids (D,E,R,K)
.Histidine and tyrosine (H,Y)


.Active site (residue annotated in Swiss-Prot as an active site)
.Predicted active site (residue aligns in a Pfam alignment with a Swiss-Prot active site)
.Predicted active site (residue annotated in Swiss-Prot as a potential active site)